Cognitive therapy in sick building syndrome: Myths, believes or evidence.

With interest, we read a recently published article by Vuokko et al. (2015) involving indoor air problems. We thank the authors for raising very important questions related to multiple health problems caused by poor indoor air. Currently, Sick Building Syndrome (SBS) is not considered as an enigmatic condition (Zhang et al., 2012). On the contrary, it has gained a lot of interest from immunologists worldwide. The SBS issue has been addressed on separate sessions every second year at the international symposia entitled ‘‘Autoimmunity’’ with several thousands of participants including clinical immunologists and basic scientists. Using advanced biochemical, immunological and genetic techniques it has been extensively documented that many substances indeed may shift the homeostasis towards morbidity status. The SBS has been now linked to an umbrella condition called Autoimmune Inflammatory Syndrome Induced by Adjuvants (ASIA) (Perricone et al., 2013). Thus, by definition, this condition causes somatic disorders, and psychological problems occur as a secondary outcome. In our opinion negative results should be published in order to minimize scientific biases. However, in relation to this article, we want to express some concerns about the study design, the results and finally about the conclusions.